International Journal Open Access

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Authors

Markus Hoffmann, Hannah Kleine‐Weber, Simon Schroeder, Nadine Krüger, Tanja Herrler, Sandra Erichsen, Tobias S. Schiergens, Georg Herrler, Nai‐Huei Wu, Andreas Nitsche

Journal

Cell

Year Published

2020

Publisher

Cell Press

Citations

20441 citations

Type

Article

Language

EN

Topics & Concepts

TMPRSS2 (0.85) Proteases (0.79) Biology (0.76) Viral entry (0.72) Virology (0.64)

Abstract

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor - Full text available via OpenAlex

Author Details

Markus Hoffmann

ORCID

Hannah Kleine‐Weber

Simon Schroeder

ORCID

Nadine Krüger

ORCID

Tanja Herrler

Sandra Erichsen

Tobias S. Schiergens

ORCID

Georg Herrler

ORCID

Nai‐Huei Wu

ORCID

Andreas Nitsche

ORCID
... and 3 more authors

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