International Journal

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Authors

Yung-Chi Cheng, William H. Prusoff

Journal

Biochemical Pharmacology

Year Published

1973

Publisher

Elsevier BV

Citations

12857 citations

Type

Article

Language

EN

Topics & Concepts

Uncompetitive inhibitor (0.96) Non-competitive inhibition (0.86) Kinetics (0.70) Enzyme kinetics (0.60) Substrate (aquarium) (0.47)

Abstract

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction - Full text available via OpenAlex

Author Details

Yung-Chi Cheng

William H. Prusoff

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