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The Sequence Alignment/Map format and SAMtools

Heng Li, Bob Handsaker, Alec Wysoker, Tim J. Fennell, Jue Ruan, Nils Homer, Gábor Marth, Gonçalo R. Abecasis, Richard M. Durbin, 1000 Genome Project Data Processing Subgroup

Bioinformatics 2009 62298 citations Open Access
Computer science Search engine indexing Sequence alignment k-mer Multiple sequence alignment

The Sequence Alignment/Map format and SAMtools - Full text available via OpenAlex

Evaluating Structural Equation Models with Unobservable Variables and Measurement Error

Claes Fornell, David F. Larcker

Journal of Marketing Research 1981 61341 citations
Unobservable Structural equation modeling Econometrics Statistics Observational error

Evaluating Structural Equation Models with Unobservable Variables and Measurement Error - Full text available via OpenAlex

Scikit-learn: Machine Learning in Python

Fabián Pedregosa, Gaël Varoquaux, Alexandre Gramfort, Michel, Vincent, Bertrand Thirion, Olivier Grisel, Mathieu Blondel, Müller, Andreas, Nothman, Joel, Louppe, Gilles

ORBi (University of Liège) 2012 61289 citations Open Access
Python (programming language) Documentation Computer science MIT License Artificial intelligence

Scikit-learn: Machine Learning in Python - Full text available via OpenAlex

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

Naruya Saitou, M Nei

Molecular Biology and Evolution 1987 59962 citations Open Access
Phylogenetic tree Tree (set theory) Biology Cluster analysis Phylogenetic network

The neighbor-joining method: a new method for reconstructing phylogenetic trees. - Full text available via OpenAlex

A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu

Stefan Grimme, Jens Antony, Stephan Ehrlich, Helge Krieg

The Journal of Chemical Physics 2010 59633 citations
Density functional theory Dispersion (optics) Ab initio Parametrization (atmospheric modeling) Intramolecular force

A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu - Full text available via OpenAlex

Gradient-based learning applied to document recognition

Yann LeCun, Léon Bottou, Yoshua Bengio, Patrick Haffner

Proceedings of the IEEE 1998 59597 citations Open Access
Computer science Artificial intelligence Convolutional neural network Intelligent character recognition Handwriting recognition

Gradient-based learning applied to document recognition - Full text available via OpenAlex

Official Methods of Analysis of

Unknown

Analytical Chemistry 1980 59407 citations
Citation Icon Altmetrics Social media Computer science

Official Methods of Analysis of - Full text available via OpenAlex

Fast and accurate short read alignment with Burrows–Wheeler transform

Heng Li, Richard M. Durbin

Bioinformatics 2009 58901 citations Open Access
Computer science Software Alignment-free sequence analysis Hash table Reference genome

Fast and accurate short read alignment with Burrows–Wheeler transform - Full text available via OpenAlex

Image quality assessment: from error visibility to structural similarity

Zhou Wang, Alan Conrad Bovik, Hamid R. Sheikh, Eero P. Simoncelli

IEEE Transactions on Image Processing 2004 58270 citations
Artificial intelligence JPEG Computer science Human visual system model Image quality

Image quality assessment: from error visibility to structural similarity - Full text available via OpenAlex

CRC Handbook of Chemistry and Physics

W.M. Haynes

CRC Press eBooks 2014 57755 citations
Chemistry Physics Engineering physics

CRC Handbook of Chemistry and Physics - Full text available via OpenAlex

Convex Optimization

Stephen Boyd, Lieven Vandenberghe

Cambridge University Press eBooks 2004 57364 citations Open Access
Appeal Subject (documents) Focus (optics) Regular polygon Convex optimization

Convex Optimization - Full text available via OpenAlex

Fast gapped-read alignment with Bowtie 2

Ben Langmead, Steven L. Salzberg

Nature Methods 2012 56834 citations Open Access
Computer science Flexibility (engineering) Dynamic programming Software Throughput

Fast gapped-read alignment with Bowtie 2 - Full text available via OpenAlex

Bias in meta-analysis detected by a simple, graphical test

Matthias Egger, George Davey Smith, Martin Schneider, C. Minder

BMJ 1997 56475 citations Open Access
Funnel plot Publication bias Meta-analysis Concordance Meta-regression

Bias in meta-analysis detected by a simple, graphical test - Full text available via OpenAlex

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann

Journal of Immunological Methods 1983 56159 citations
Cytotoxicity Formazan Colorimetry Lysis Molecular biology

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays - Full text available via OpenAlex

Distinctive Image Features from Scale-Invariant Keypoints

David G. Lowe

International Journal of Computer Vision 2004 56079 citations
Artificial intelligence Pattern recognition (psychology) Clutter Affine transformation Computer science

Distinctive Image Features from Scale-Invariant Keypoints - Full text available via OpenAlex

Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks

Shaoqing Ren, Kaiming He, Ross Girshick, Jian Sun

IEEE Transactions on Pattern Analysis and Machine Intelligence 2016 55735 citations
Computer science Object detection Artificial intelligence Computer vision Object (grammar)

Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks - Full text available via OpenAlex

Global cancer statistics

Ahmedin Jemal, Freddie Bray, Jacques Ferlay, Elizabeth Ward, David Forman

CA A Cancer Journal for Clinicians 2011 54766 citations Open Access
Medicine Statistics Cancer incidence Incidence (geometry) Cancer

Global cancer statistics - Full text available via OpenAlex

Density-functional exchange-energy approximation with correct asymptotic behavior

Axel D. Becke

Physical Review A 1988 53835 citations
Hybrid functional Limit (mathematics) Physics Density functional theory Energy (signal processing)

Density-functional exchange-energy approximation with correct asymptotic behavior - Full text available via OpenAlex

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Harry Towbin, Th. Staehelin, J Gordon

Proceedings of the National Academy of Sciences 1979 53773 citations Open Access
Nitrocellulose Polyacrylamide Chemistry Peroxidase Urea

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. - Full text available via OpenAlex

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind N. Subramanian, Pablo Tamayo, Vamsi Krishna Mootha, Sayan Mukherjee, Benjamin L. Ebert, Michael A. Gillette, Amanda G. Paulovich, Scott L. Pomeroy, Todd R. Golub, Eric S. Lander

Proceedings of the National Academy of Sciences 2005 53751 citations Open Access
Computational biology Gene Biology Function (biology) Gene expression

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles - Full text available via OpenAlex

Mind in Society: The Development of Higher Psychological Processes

L. S. Vygotsky

Medical Entomology and Zoology 1978 53637 citations
Symbol (formal) Perception Psychology Index (typography) Cognitive science

Mind in Society: The Development of Higher Psychological Processes - Full text available via OpenAlex

Inhomogeneous Electron Gas

Pierre C. Hohenberg, Walter Kohn

Physical Review 1964 53509 citations Open Access

Inhomogeneous Electron Gas - Full text available via OpenAlex

The CES-D Scale

Lenore Sawyer Radloff

Applied Psychological Measurement 1977 53441 citations Open Access
Psychology Scale (ratio) Construct validity Reliability (semiconductor) Test validity

The CES-D Scale - Full text available via OpenAlex

XGBoost

Tianqi Chen, Carlos Guestrin

ACM SIGKDD International Conference on Knowledge Discovery and Data Mining (KDD) 2016 53305 citations Open Access
Boosting (machine learning) Computer science Scalability Machine learning Sketch

XGBoost - Full text available via OpenAlex

Colorimetric Method for Determination of Sugars and Related Substances

Michel. DuBois, K. A. Gilles, J. Kelvin Hamilton, Paul A. Rebers, F. Smith

Analytical Chemistry 1956 52320 citations
Citation Icon Altmetrics Social media Computer science

Colorimetric Method for Determination of Sugars and Related Substances - Full text available via OpenAlex

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